Make it VIZZable

with VIZZ, a once-daily prescription eye drop that gives you the power to restore near vision for up to 10 hours¹

The most common reported adverse reactions of participants were installation site irritation (20%), dim vision (16%), and headache (13%). Adverse reactions reported in >5% of participants were conjunctival hyperemia (8%) and ocular hyperemia (7%). The majority of adverse reactions were mild, transient, and self-resolving.

VIZZ is an aceclidine-based eye drop that selectively targets the pupil¹

Aceclidine, the active ingredient in VIZZ¹:

EyeIs a pupil-selective miotic

EyeAvoids overstimulating the ciliary muscle

Instillation site irritation was reported in 20% of study participants. The majority of adverse reactions were mild, transient, and self-resolving.

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99%

of patients achieved the ideal pupil size (<2mm) to restore near vision²

% of Participants Achieving ≥2- and ≥3-Line Near Vision Improvement1,2

Day 1, CLARITY 2, full analysis set (VIZZ: n=77; vehicle: n=76). 3-line vehicle 5%-12%, 2-line vehicle 17%-24%. CLARITY 2 trial: Near visual acuity was assessed at 40cm using monocular DCNVA (distance-corrected near visual acuity). CLARITY was a Phase 3, multicenter, double-masked, randomized, controlled efficacy and safety study of VIZZ (1.44% aceclidine) for the treatment of presbyopia. The primary efficacy endpoint was the percentage of patients who achieved ≥3 lines of improvement in DCNVA without losing 1 line (5 letters) or more of distance vision at 3 hours post treatment on Day 1. VIZZ achieved all primary and secondary endpoints (in all cases, P<0.0001).¹,²

Patients may experience dim or dark vision. Dim vision was reported in 16% of study participants.

VIZZ lasts up to 10 hours with a once-daily dose¹

  • 91%

    of patients improved their near vision by at least 2 lines within 30 minutes²

  • 69%

    of patients improved their near vision by at least 2 lines at 10 hours²

Functional near vision: 93% achieved 20/40 or better near vision at 30 minutes, 69% at 10 hours2

Day 1, Clarity 1 & 2, Analysis of Binocular Distance Corrected Near Vision with logMAR ≤ 0.3 (~20/40 or J3)

Patients may experience dim or dark vision. Dim vision was reported in 16% of study participants.

VIZZ achieves functional near vision for up to 10 hours

~7 out of 10

patients achieved 20/40 (J3) at 10 hours

Once-daily VIZZ is simple for patients to use¹:

  • Instill one drop in each eye, wait 2 minutes and instill a second drop in each eye once daily from the same single-dose vial.

  • If more than one topical ophthalmic drug is being used, the drugs should be administered at least 5 minutes apart.

  • Contact lenses should be removed prior to instillation of VIZZ and may be reinserted 10 minutes following its administration.

  • No contraindications.

VIZZ is well tolerated¹

  • No serious treatment-related adverse events¹

  • Most adverse events were mild and temporary¹

The most common reported adverse reactions of participants were instillation site irritation (20%), dim vision (16%), and headache (13%). Adverse reactions reported in >5% of participants were conjunctival hyperemia (8%) and ocular hyperemia (7%). The majority of adverse reactions were mild, transient, and self-resolving.

Who is VIZZ right for?

The majority of presbyopes would seriously consider a new presbyopia solution.² Who should you prioritize?

Patient Profile 1
Patient Profile 2
Patient Profile 3

Headaches were reported in 13% of study participants. The majority of adverse reactions were mild, transient, and self-resolving.

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Eye redness was reported in 15% of study participants.

VIZZ is easy to

access.

Send VIZZ prescriptions to UpScript

Patients can save the most with UpScript

791-month supply (25 vials)
198
($66/month)
Save more with a 3-
month supply (75 vials)

Cash pay with no prior authorization required.

VIZZ is the first and only aceclidine-based eye drop for presbyopia1,4

Powered by aceclidine1

Achieves ideal <2mm pupil size for clear near vision2

Lasts up to 10 hours with once-daily dosing1

Well tolerated, with no serious treatment-related adverse events1

Easy to access through UpScript or local pharmacies.

Sequelae of ocular inflammation, i.e., adhesions (synechiae) between the iris and the lens, may be exacerbated with miotic use in patients with a known history of iritis.